The only reason you are likely to visit Villazón is if you intend on leaving Bolivia, or have just arrived from Argentina, as this town is where the main border crossing between these two countries is located. As far as South American frontier towns go, this one is relatively harmless, and a bustling, but usually trouble free place to start (or end) your trip in Bolivia.
Villazón is an extremely easy town to navigate around. It has everything you will need, starting with the train station, then the bus station (where the tourist police are located), a tourist information booth (where free, basic, photocopied, maps are available, Tel: 02-597-2119), an ATM and finally the border crossing, all situated along one long main street, Avenida Republica Argentina. Although few tourists choose to stay the night here, you may find yourself stuck, and this main street is also where the best accommodation, restaurants and shops are located. The unmissable blue glass Gran Hotel Olimpo (on the corner of Av. Republica Argentina and Chorolque, Tel: 02-596-5302), conveniently located near the border provides the best and most expensive rooms in town (with / without private bathrooms: singles 55 / 75 Bs., doubles 100 / 150 Bs., matrimonials 95 / 120 Bs.). Just across the road Hotel Avendida (Av. Republica Argntina 228, Tel: 02-597-2946) has cheaper, clean and adequate rooms (singles 30 Bs., doubles 50 Bs. with shared bathrooms). If you are on a tight budget, cheaper hotels can easily be found off the main street, although their quality decreases rapidly. Alternatively, try over the border in La Quiaca for a greater variety of higher quality though correspondingly higher priced accommodations.