The main access to Huilo-Huilo Biological Reserve is from Panguipulli along the Huahum Passage, that leads to San Martin de los Andes.
Access to the park is from the route that leaves Temuco and passes through Villarrica, Lican Ray, CoƱaripe and Neltume Lake. It is a distance of 170 kilometers (106 mi).
By air: arrive at the Choshuenco Airport, located 14 kilometers (9 mi) from the reserve or Temuco Airport 190 kilometers (118 mi)

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