No buses or cars for you, luxury travelers! If money is no object, you'll definitely want to arrange a very complete tour that includes all transfers and trips. Buses in Ecuador are convenient, comfortable and cheap, but they can be somewhat limiting and dealing with them will take up valuable time: if you can afford it, going with a tour is definitely the way to go.
Also, if you're traveling to the Oriente â€“ the rainforest â€“ you may have the option of overland or air travel to Coca or Lago Agrio. The overland trip is interesting but long and somewhat grueling, as the roads are terrible. Flying will also change a ten-hour trip to 45 minutes: big difference.